Welcome! I am an assistant professor in the Department of Mathematics at Ohio State University. My primary research area is in modeling infectious disease dynamics, with a particular emphasis on waterborne diseases. Much of my recent work concerns cholera dynamics. I am also interested in neuroscience, and parameter estimation for differential equations.
- Eisenberg MC, Robertson SL, Tien JH. 2013. Identifiability and estimation of multiple transmission pathways in cholera and waterborne disease. Journal of Theoretical Biology. 324: 84-102.
- Shuai Z, Tien JH, van den Driessche P. 2012. Cholera models with hyperinfectivity and temporary immunity. Bulletin of Mathematical Biology. 74(10): 2423-2445. doi: 10.1007/s11538-012-9759-4.
- Holte S, Randolph T, Ding J, Tien JH, McClelland R, Baeten J, Overbaugh J. 2012. Efficient use of longitudinal CD4 counts and viral load measures in survival analysis. Statistics in Medicine. 31(19): 2086-2097. doi: 10.1002/sim.5318.
- Tuite AR, Tien JH, Eisenberg MC, Earn DJD, Ma J, Fisman DN. 2011. Cholera epidemic in Haiti, 2010 - using a transmission model to explain spatial spread of disease and identify optimal control interventions. Annals of Internal Medicine. 154(9): 593-601.
- Tien JH, Poinar HN, Fisman DN, Earn DJD. 2011. Herald waves of cholera in 19th century London. Journal of the Royal Society Interface 8(58): 756-760. doi:10.1098/rsif.2010.0494.
- Lyles D, Tien JH, McCobb DP, Zeeman ML. 2010. Pituitary network connectivity as a mechanism for the LH surge. Journal of Neuroendocrinology 22(12): 1267-1278.
- Tien JH, Earn DJD. 2010. Multiple transmission pathways and disease dynamics in a waterborne pathogen model. Bulletin of Mathematical Biology 72(6): 1506-1533.
- Tien JH, Guckenheimer J. 2008. Parameter estimation for bursting neural models. Journal of Computational Neuroscience 24(3): 358-373.
- Guckenheimer J, Tien JH. 2007. Commentary on "Parameter estimation for differential equations: a generalized smoothing approach" by Ramsay JO, Hooker G, Campbell D, Cao J. Journal of the Royal Statistical Society B 69(5): 741-770.
- Guckenheimer J, Tien JH, Willms AR. 2005. Bifurcations in the fast dynamics of neurons: implications for bursting. In: Bursting: the genesis of rhythm in the nervous system. (Eds.) Coombes S, Bresloff PC. World Scientific Press, pp. 91-124.
- Tien JH, Hazelton WD, Sparks R, Ulrich CM. 2005. A Michaelis-Menten-style model for the autocatalytic enzyme prostaglandin H synthase. Bulletin of Mathematical Biology 67: 683-700.
- Tien JH, Lyles D, Zeeman ML. 2005. A potential role of modulating inositol 1,4,5-trisphosphate receptor desensitization and recovery rates in regulating ovulation. Journal of Theoretical Biology 232(1): 105-117.
- Hazelton WD, Tien JH, Donato VW, Sparks R, Ulrich CM. 2004. Prostaglandin H syntases: members of a class of quasi-linear threshold switches. Biochemical Pharmacology 68(3): 423-432.
- Tien JH, Levin SA, Rubenstein DI. 2004. Dynamics of fish shoals: identifying key decision rules. Evolutionary Ecology Research 6: 555-565.
I am teaching math 1157 in Spring 2013. Some courses I have taught previously are listed below:
- Autumn 2012: Mathematical topics for engineers (Math 2177).
- Winter 2012, Spring 2011: Ordinary and partial differential equations (Math 415).
- Fall 2010: Topics in mathematical ecology (co-taught with Yuan Lou, Libby Marschall, Ian Hamilton).
- Spring 2009: Differential equations III (Math 617).
- Winter 2009: Introduction to real analysis (Math 547).
Post-docs interested in working with me are encouraged to apply for the three year postdoctoral fellowships at the Mathematical Biosciences Institute (MBI) here at Ohio State.
Interested graduate students can apply to either the math department's Ph.D. program or the Master's program in mathematical biology. I currently have an opening for a PhD student as part of a NSF grant on modeling cholera dynamics. An overview of all graduate programs in the department can be found here.
Undergraduates at OSU can pursue research in mathematical biology through the RUMBA program. MBI also holds an annual summer program on mathematical biology for undergraduates. This latter program is open to undergraduates outside of Ohio State as well.